Publications
June 9 2024
Applying Flow Virometry to Study the HIV Envelope Glycoprotein and Differences Across HIV Model Systems
Burnie J, Fernandes C, Patel A, Persaud AT, Chaphekar D, Wei D, Lee TKH, Tang VA, Cicala C, Arthos J, Guzzo C. Applying Flow Virometry to Study the HIV Envelope Glycoprotein and Differences Across HIV Model Systems. Viruses. 2024 Jun 9;16(6):935. doi: 10.3390/v16060935. PMID: 38932227; PMCID: PMC11209363.
May 14 2024
Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells
Persaud AT, Khela J, Fernandes C, Chaphekar D, Burnie J, Tang VA, Colpitts CC, Guzzo C. Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells. J Virol. 2024 May 14;98(5):e0036324. doi: 10.1128/jvi.00363-24. Epub 2024 Apr 25. PMID: 38661384; PMCID: PMC11092368.
December 27 2023
Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay
\Burnie J, Fernandes C, Chaphekar D, Wei D, Ahmed S, Persaud AT, Khader N, Cicala C, Arthos J, Tang VA, Guzzo C. Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay. Sci Rep. 2023 Dec 27;13(1):23025. doi: 10.1038/s41598-023-50365-0. PMID: 38155248; PMCID: PMC10754950
Jonathan Burnie, Arvin T. Persaud, Laxshaginee Thaya, Qingbo Liu, Huiyi Miao, Stephen Grabinsky, Vanessa Norouzi, Paolo Lusso, Vera A. Tang, Christina Guzzo. P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells. Retrovirology. 2022 May 21;19(1):9. doi: 10.1186/s12977-022-00593-5.PMID: 35597982
May 21, 2022
P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells.
Jonathan Burnie, Arvin T. Persaud, Laxshaginee Thaya, Qingbo Liu, Huiyi Miao, Stephen Grabinsky, Vanessa Norouzi, Paolo Lusso, Vera A. Tang, Christina Guzzo. P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells. Retrovirology. 2022 May 21;19(1):9. doi: 10.1186/s12977-022-00593-5.PMID: 35597982
February 10, 2022
A UV-LED module that is highly effective at inactivating human coronaviruses and HIV-1
Persaud, A.T., Burnie, J., Thaya, L. et al. A UV-LED module that is highly effective at inactivating human coronaviruses and HIV-1. Virol J 19, 29 (2022). https://doi.org/10.1186/s12985-022-01754-w
June 11, 2021
Human monocytes store and secrete preformed CCL5, independent of de novo protein synthesis
Persaud AT, Bennett SA, Thaya L, Burnie J, Guzzo C. Human monocytes store and secrete preformed CCL5, independent of de novo protein synthesis. Journal of Leukocyte Biology. 2021 Jun. DOI: 10.1002/jlb.3a0820-522rr.
November 12, 2020
Flow Virometry Quantification of Host Proteins on the Surface of HIV-1 Pseudovirus Particles
Burnie, J., Tang, V.A., Welsh, J.A., Persaud, A.T., Thaya, L., Jones, J.C., & Guzzo, C. (2020). Flow Virometry Quantification of Host Proteins on the Surface of HIV-1 Pseudovirus Particles. Viruses, 12(11), 1296. doi:https://doi.org/10.3390/v12111296
May 29, 2019
Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review
Hamidzada, H., & Guzzo, C. (2019). Pleiotropic Roles of Cytokines in HIV-1 Pathogenesis and Control: A Literature Review. Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal, 3 (5), 1-10. doi:10.26685/urncst.128
January 20, 2019
The Incorporation of Host Proteins into the External HIV-1 Envelope
Burnie, J., & Guzzo, C. (2019). The Incorporation of Host Proteins into the External HIV-1 Envelope. Viruses, 11 (1), 85. doi:10.3390/v11010085
December 11, 2018
Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation
Guzzo, C., Zhang, P., Liu, Q., Kwon, A. L., Uddin, F., Wells, A. I., . . . Lusso, P. (2018). Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation. MBio,9(6). doi:10.1128/mbio.00955-18
May 12, 2017
Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing.
Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing. Guzzo C, Ichikawa D, Park C, Phillips D, Liu Q, Zhang P, Kwon A, Miao H, Lu J, Rehm C, Arthos J, Cicala C, Cohen MS, Fauci AS, Kehrl JH, Lusso P. Sci Immunol. 2017 May 12;2(11). pii: eaam7341. doi: 10.1126/sciimmunol.aam7341.